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The mysterious death of Alexander the Great


    When Alexander the Great’s body seemingly remained unchanged for six days after his death in 323 BCE, his contemporaries could offer only one explanation. Alexander must have been a god. So… was he?

    Alexander the Great first fell ill during a days-long series of parties, during one of which he collapsed, complaining of a searing pain in his back. After 10 days of intense fever, Alexander’s soldiers were brought in to see him one final time. As reported by the historian Arrian, at that point the king “could no longer speak… but he struggled to raise his head and gave each man a greeting with his eyes.”

    When Alexander was declared dead on June 13, theories began forming. Had he been poisoned? Sabotaged? Had he been killed by drinking too much wine? Today we have an explanation for Alexander’s death and his period of bodily freshness that relies less on the supernatural and more on science. In 2018 Dr. Katherine Hall, a lecturer in New Zealand, proposed that Alexander the Great had Guillain-Barré syndrome, an acute autoimmune condition that results in muscle paralysis. In other words, Alexander may have been alive when he was declared dead—a mistake that could have been made when physicians mistook the shallow breathing of a coma patient for no breathing at all. If this was the case, Alexander may have been effectively murdered during embalming—a process that would have seen him disemboweled.

    While we can’t travel back in time to confirm Hall’s theory, it is the only one that takes into account all the details of Alexander’s death—and his body’s mysterious life.


Encyclopaedia Britannica. Adaptation 

Throughout the text, an apostrophe and “s” are seen. What does that indicate? 

Muitos fármacos necessitam sofrer biotransformação em formas mais polares para que sejam eliminados do corpo. As reações de biotransformação são designadas como reações da fase I, que tornam o agente mais polar através de oxidação, redução ou hidrólise. Em termos quantitativos, as enzimas da fase I de maior importância são os citocromos P450, uma superfamília de proteínas contendo heme, que catalisam o metabolismo de muitas substâncias lipofílicas. As isozimas do citocromo P450 denominam-se CYP e são agrupadas pelo grau de identidade na sua sequência de aminoácidos. Nesse contexto, assinalar a alternativa que se refere ao padrão de desenvolvimento para enzimas citocromo P450 importantes no recém-nascido: 


Não aparentes no fígado fetal. Dados inferenciais, utilizando o processamento da fenitoína como sonda farmacológica inespecífica, sugerem atividade baixa durante a primeira semana devida, sendo a atividade de adulto alcançada até os 6 meses de idade, com atividade máxima até os 3 a 4 anos de idade. Metabolismo induzido por rifampicina e fenobarbital e inibido por cimetidina. 

The mysterious death of Alexander the Great


    When Alexander the Great’s body seemingly remained unchanged for six days after his death in 323 BCE, his contemporaries could offer only one explanation. Alexander must have been a god. So… was he?

    Alexander the Great first fell ill during a days-long series of parties, during one of which he collapsed, complaining of a searing pain in his back. After 10 days of intense fever, Alexander’s soldiers were brought in to see him one final time. As reported by the historian Arrian, at that point the king “could no longer speak… but he struggled to raise his head and gave each man a greeting with his eyes.”

    When Alexander was declared dead on June 13, theories began forming. Had he been poisoned? Sabotaged? Had he been killed by drinking too much wine? Today we have an explanation for Alexander’s death and his period of bodily freshness that relies less on the supernatural and more on science. In 2018 Dr. Katherine Hall, a lecturer in New Zealand, proposed that Alexander the Great had Guillain-Barré syndrome, an acute autoimmune condition that results in muscle paralysis. In other words, Alexander may have been alive when he was declared dead—a mistake that could have been made when physicians mistook the shallow breathing of a coma patient for no breathing at all. If this was the case, Alexander may have been effectively murdered during embalming—a process that would have seen him disemboweled.

    While we can’t travel back in time to confirm Hall’s theory, it is the only one that takes into account all the details of Alexander’s death—and his body’s mysterious life.


Encyclopaedia Britannica. Adaptation 

The tense and aspect of the underlined verbs below are:


Alexander the Great first fell ill during a days-long series of parties, during one of which he collapsed, complaining of a searing pain in his back. After 10 days of intense fever, Alexander’s soldiers were brought in to see him one final time. As reported by the historian Arrian, at that point the king “could no longer speak… but he struggled to raise his head and gave each man a greeting with his eyes.”

Mulher de 26 anos, hígida, moradora de uma cidade do interior, chega ao consultório aflita com diagnóstico de gestação. Relata sentir-se ansiosa e com medo de não saber como será sua gestação, já que é mãe de primeira viagem. Após acolhê-la e iniciar seu pré-natal, o médico da Unidade Básica de Saúde precisa orientar a mãe quanto aos próximos nove meses. A respeito do pré-natal, assinalar a alternativa CORRETA.  

Homem, 45 anos, trabalha em contato direto com colas, tintas e fluidos de transmissão. Refere tontura, cefaleia, letargia e náuseas há 48 horas. Assinalar a alternativa que apresenta a hipótese mais provável para esse caso. 

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